Dunleavy connected on 11-of-17 from the field as six Pacers finished in double figures. Danny Granger added 23, while Jamal Tinsley finished with 14 points and seven assists. Jermaine O'Neal scored 13, and Kareem Rush and Ike Diogu chipped in 12 each.
Kyle Lowry led Memphis with a career-high 19 points and Pau Gasol finished with 18. Mike Miller scored 14 and Rudy Gay finished with 13 in 19 minutes after struggling through foul trouble. Gasol and Miller had 10 rebounds each.
Memphis, which never led in the game, had finally cut into the Pacers' double-digit lead during the latter part of the third period. Indiana scored the first nine points of the fourth to rebuild the advantage to 16.
The Grizzlies had one run left midway through the period when they went on an 11-0 run to get to 105-101. A basket by Dunleavy and a pair of field goals by Diogu put an end to the streak, and Indiana was in front to stay.
The Grizzlies' 27 turnovers led to 36 points.
Read Chris Herrington's GrizBlog, Beyond the Arc, for more analysis of the game.